The anchorage was evaluated based on the calculated contact area between the stent’s outer frame with the native CAV over time. Three implantation depth locations (aortic, midway, and ventricular) following the manufacturer guidelines were modeled to study the valve anchorage. Materials and Methods: LHHM is an electro-mechanical model of heart function in which a self-expandable TAVR valve (Evolut R Medtronic, Inc.) implantation procedures were simulated using finite element modeling (Abaqus Explicit 6.14 Dassault Systèmes). This study utilizes Simulia Living Heart Human Model (LHHM) heart beating capabilities coupled with a fluid-structure interaction (FSI) simulation to evaluate TAVR complications. Previous numerical studies attempted to address these complications but neglected the valve post-deployment performances during heart beating. However, valve migration, paravalvular leakage (PVL), and thrombogenic potential may limit its expansion into younger, lower-risk patients. Transcatheter aortic valve replacement (TAVR) has emerged as a life-saving solution for inoperable elderly patients with end-stage calcific aortic valve (CAV) disease.
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